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Study finds estrogen-only hormone therapy linked to fewer signs of Alzheimer's

ScienceDaily · first seen 14.08.2026

A large study of over 21,000 participants found that women using estrogen-only hormone therapy later in life had lower odds of dementia and fewer Alzheimer's-related brain changes.

  • Study included more than 21,000 participants
  • Hormone therapy linked to 39% lower odds of dementia diagnosis
  • Associated with 35% lower odds of Alzheimer's-related brain changes at autopsy
  • Biomarker tests showed less amyloid buildup among users

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